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Core-shell microparticles based on acrylic ion exchange resin/polysaccharides as drug carriers
Authors: S. Vasiliu, I. Bunia, V. Neagu
Affiliation: “Petru Poni” Institute of Macromolecular Chemistry, Grigore Ghica Voda 41A, 700487, Iasi, Romania
Published in: Ion Exch. Lett. 2010, 2(3), 27-30
Permanent link to this page: http://iel.vscht.cz/abstracts/1803-4039-02-0027.htm
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Keywords: core-shell microparticles, acrylic ion exchange resin, gellan, xanthan, drug release
Abstract: Core-shell microparticles consisted of acrylic ion exchange resin as the core and two natural polymers (gellan or xanthan) as the shell are presented in this paper. These new polymeric materials were characterized by FT IR spectroscopy, optical microscopy and swelling degree in water. Taking into account the possibility of their use in the medical and pharmaceutical fields, the retention and release capacities of cefotaxime sodium salt were investigated.